Microdosing psilocybin mushrooms can potentially be helpful for those looking to taper off of psychotropic medications such as antidepressants, anti-anxiety medications, stimulants, antipsychotics, and mood stabilizers. 

 

This is because psilocybin binds to the 5-HT receptors which are linked to mood, social behavior, sexual desire, memory, sleep, appetite and digestion among many other things. In other words, the benefit to including microdoses of psilocybin while tapering off of pharmaceuticals is that it provides a natural supplement to the systems influenced by psychotropic medications.

 

This effect lessens or even eliminates the pharmaceutical withdrawal side effects altogether (things like brain zaps, fatigue, irritability, etc.). Many people report feeling lighter and more alive while taking microdoses with their psychotropic medications, even while tapering.

 

The other benefit to microdosing during the tapering process is that it increases neuroplasticity in the brain. Although microdosing effects are sub-perceptual, they allow for the brain to form and reorganize synaptic connections. 

 

In other words, a microdosing protocol allows the brain to be re-wired in a way such that it is not dependent on pharmaceutical medications. In summary, microdosing psilocybin potentially allows one to taper off of their psychotropic medications faster and with far fewer withdrawal side.

 

Now that there is a basic understanding of the relationship between microdosing psilocybin and tapering down or off of psychotropic medications, the next logical question is how to actually taper off of pharmaceuticals.